Basic biomedical and translational research projects funded by the Heart and Stroke Foundation of BC & Yukon, the Canadian Institutes of Health Research, the Natural Sciences and Engineering Research Council of Canada, and the Michael Smith Foundation for Health Research. Heart valve study with Wyeth Ayerst leading to GlaxoSmithKline’s evaluation of new anti-obesity drugs in 1998. Projects funded by other multi-national pharmaceutical companies including Eli Lilly, Novartis, and biotech companies. Structure and function evaluations of new interventional devices including Edwards Lifesciences. Biomarker discovery in collaboration with the PROOF Centre of Excellence.